ChemicalBook > CAS DataBase List > 3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid
3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid
- Product Name
- 3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid
- CAS No.
- 196961-43-0
- Chemical Name
- 3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid
- Synonyms
- CD 3254;CD3254,CD-3254;3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid;2-Propenoic acid, 3-[4-hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-
- CBNumber
- CB72518841
- Molecular Formula
- C24H28O3
- Formula Weight
- 364.48
- MOL File
- 196961-43-0.mol
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3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid Property
- Melting point:
- 165 - 167°C
- Boiling point:
- 508.0±50.0 °C(Predicted)
- Density
- 1.108±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 4.61±0.10(Predicted)
- color
- White to Off-White
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 20870
- Product name
- CD3254
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $33
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 20870
- Product name
- CD3254
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $123
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 20870
- Product name
- CD3254
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $213
- Updated
- 2024/03/01
Tocris
- Product number
- 3302
- Product name
- CD3254
- Purity
- ≥97%(HPLC)
- Packaging
- 10
- Price
- $233
- Updated
- 2021/12/16
Tocris
- Product number
- 3302
- Product name
- CD3254
- Purity
- ≥97%(HPLC)
- Packaging
- 50
- Price
- $952
- Updated
- 2021/12/16
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3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid Chemical Properties,Usage,Production
Description
CD3254 is a selective agonist of the retinoid X receptors (RXRs; EC50 = ~10 nM for human RXRβ) that is without effect on retinoic acid receptors (RARs). It stimulates the recruitment of the nuclear receptor interaction domain of the TRAP220 coactivator to RXRα/RARβ heterodimers in vitro. CD3254 also enhances the recruitment of the PPARγ coactivator 1α, PGC-1α, to RXRα/PPARγ heterodimers.
Uses
CD 3254 is a potent RXR agonist.
storage
Store at -20°C
3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid Preparation Products And Raw materials
Raw materials
Preparation Products
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